Get the Facts on Myelofibrosis
Myelofibrosis is a rare bone marrow cancer in which the marrow is replaced by fibrous (scar) tissue. Myelofibrosis can occur on its own, called primary myelofibrosis, or as a progression of other bone marrow diseases. Myelofibrosis belongs to a group of closely related blood cancers, known as myeloproliferative neoplasms, in which the bone marrow cells that produce the body’s blood cells develop and function abnormally. The result is excessive fibrous tissue formation in the bone marrow, which can lead to severe anemia, weakness, fatigue, and an enlarged spleen and liver.
Questions and Answers about Lymphedema
by Stanley G. Rockson, MD, FACP, FACC
Lymphedema is the accumulation of a protein-rich body fluid called lymph, typically in one part of the body, when the lymphatic system for fluid transport is damaged. For example, if lymph nodes are removed from the armpit region during breast cancer treatment, lymphedema can occur in that arm.
Chronic lymphocytic leukemia is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). CLL, a slow-growing blood and bone marrow disease, is one of the most common types of leukemia in adults.
How Is Chronic Myeloid Leukemia Treated?
Treatment options and recommendations for people with chronic myeloid leukemia depend on several factors, including the phase of the disease, possible side effects, and your preferences and overall health. Take time to learn about your treatment options, and be sure to ask questions about things that are unclear. Also, discuss the goals of each treatment with your doctor and ask what you can expect while receiving the treatment.
FDA Approves Gazyva for Chronic Lymphocytic Leukemia
The U.S. Food and Drug Administration has approved Gazyva (obinutuzumab) for use in combination with chlorambucil to treat patients with previously untreated chronic lymphocytic leukemia (CLL). Gazyva works by helping certain cells in the immune system attack cancer cells. Gazyva is intended to be used with chlorambucil, another drug used to treat patients with CLL.
Treating Chronic Myelogenous Leukemia
Different types of treatment are available for people with chronic myelogenous leukemia (CML). Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. The six types of standard treatment used to treat CML are targeted therapy, chemotherapy, biologic therapy, high-dose chemotherapy with stem cell transplant, donor lymphocyte infusion, and surgery.
FDA Approves Iclusig to Treat Two Rare Types of Leukemia
The U.S. Food and Drug Administration has approved Iclusig (ponatinib) to treat adults with chronic myeloid leukemia (CML) and Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL), two rare blood and bone marrow diseases. Iclusig is being approved more than three months ahead of the product’s prescription user fee goal date.
Realistic Optimism in Cancerville
by William Penzer, PhD
Not knowing what will happen brings out the frightened, confused, and overwhelmed parts of us in all life’s areas, and especially in Cancerville. The philosophy of realistic optimism seeks to offset our automatic pessimistic reactions. It strives to replace hopelessness with hopefulness, within realistic boundaries.