After Treatment for Prostate Cancer
Managing Side Effects
You may feel
embarrassed
talking about
some of these
side effects, but
remember that
your doctor is
there to help you
feel better and live
as comfortably as
possible.
Some men who receive treatment for prostate cancer have side effects caused by treatment. These side effects may include incontinence (the inability to control urination), bowel problems, impotence (the inability to get an erection), infertility (the inability to father a child), hormonal changes, and side effects of chemotherapy, such as fatigue. Men receiving treatment for prostate cancer may have one or more of these side effects. However, not every man has every side effect; some men have few or none. Talk with your doctor to learn more about your risk of side effects.
It is important to let your doctor know if cancer treatment is causing any side effects. You may feel embarrassed talking about some of these side effects, but remember that your doctor and the healthcare team are there to help you feel better and live as comfortably as possible. Support services, such as support groups and counseling, may also help. Talk with your doctor or nurse about services available to help you manage any of the side effects discussed below.
Incontinence
Surgery to remove
the prostate can cause incontinence,
a common side effect of prostate cancer
treatment. Incontinence may be
short-term (temporary) or long-term
(permanent). There are four types of
incontinence. Stress incontinence is
the most common type of incontinence
after prostate surgery. Men with stress
incontinence leak urine when they cough,
laugh, sneeze, or exercise. Men with
overflow incontinence take a long time
to urinate and have a dribbling stream
of urine. Men with urge incontinence
have a sudden need to urinate. In rare
cases, men lose all ability to control
their urine. This condition is called
continuous incontinence.
If you have incontinence, limit the amount of coffee and alcohol you drink, and urinate before bedtime and before strenuous activity. Techniques called Kegel exercises tone the muscles that hold urine. You perform Kegel exercises by tightening or clenching the muscles in your pelvis. When you tighten your muscles to stop the flow of urine or to prevent passing gas, you are doing a Kegel exercise. A technique called biofeedback and electrical stimulation can help you do better Kegel exercises. Ask your doctor for more information about Kegel exercises and biofeedback.
Medications, such as oxybutynin (Ditropan) and tolterodine (Detrol), can help with both stress incontinence and urge incontinence. Talk with your doctor about the use of medications to treat incontinence. To control leakage, wear an absorbent pad inside your underwear. You can buy pads at your local grocery store or drugstore. Surgery to increase the size of the bladder or surgery to implant an artificial urinary sphincter (a valve that controls the flow of urine from the bladder) may be treatment options for permanent incontinence. Talk with your doctor if your incontinence does not improve.
For some men, impotence is temporary and goes away after time. If you have had surgery to remove your prostate, impotence is more likely to be permanent.
Bowel Problems
Some men with
prostate cancer who receive radiation
treatment may have bowel problems during
and after treatment. These problems
are more commonly caused by external
beam radiation than brachytherapy or
internal radiation therapy. Possible
bowel problems are diarrhea, gas, loss
of control of bowel movements, and
bleeding with bowel movements.
Many men are able to manage bowel problems by taking over-the-counter medications. Most of these problems go away over time, but sometimes, normal bowel function does not return after treatment ends. Talk with your doctor about any bowel problems you are having.
Impotence
Impotence is also called
erectile dysfunction (ED). Surgery, radiation
therapy, or hormone therapy can
cause some men to become impotent.
For some men, impotence is temporary and goes away after time. If you have had surgery to remove your prostate, impotence is more likely to be permanent. If you have impotence caused by hormone therapy, your ability to have an erection may improve after your treatment ends. If you have been treated with radiation therapy, you may not have any signs of impotence until months after your treatment ends.
Coping with impotence may be difficult. The following methods may help you manage impotence and achieve erections:
- Medications, such as sildenafil (Viagra), vardenafil (Levitra), or tadalafil (Cialis);
- A medication called alprostadil (Caverject, Edex, Muse) that you inject in the skin at the base of the penis before sex. Pellets of alprostadil can also be inserted into the penis through the urethra;
- A tube called a vacuum constriction device that you place over the penis to create suction, which may also help you get an erection; and
- A prosthesis (artificial implant) that is surgically placed into the penis.
Talk with your doctor about these options and ask about available support services. In addition, talking with your partner and finding counseling may help both of you cope with this problem.
Infertility
Surgery, radiation treatment,
and chemotherapy may cause
temporary or permanent infertility in
men being treated for prostate cancer.
Medical procedures done before treatment,
such as sperm banking, help
prevent infertility. However, there are
options and medical procedures available
to men who remain infertile after
cancer treatment and who did not undergo
any methods to preserve fertility
before starting treatment. An example
of one procedure is called testicular
sperm extraction. In this procedure,
sperm cells found in tissue removed from
a man’s testicles are used in a fertility
procedure or frozen for later use.
Hormonal Changes
Many men
with prostate cancer who are treated
with hormone therapy have side effects
related to this treatment. Common side
effects are impotence and a decreased
desire to have sex. Many men treated
with hormones also have side effects
that are similar to women going through
menopause, including hot flashes, growth
of breast tissue, depression, weight gain,
loss of muscle mass, osteoporosis (bone
thinning), which can cause broken bones,
and low red blood cell counts, which
can cause anemia (a condition that can
make you feel tired). The risk of high
blood pressure, diabetes, and heart attacks
is also higher in men treated with
hormone therapy.
Many of these side effects can be prevented or treated. Hot flashes can be helped by treatment with hormones, antidepressants, and a drug called gabapentin (Neurontin). A small amount of radiation treatment to the breasts can help prevent them from growing. Medications called bisphosphonates help treat osteoporosis. Examples include alendronate (Fosamax) and zoledronic acid (Zometa). Depression can be treated by antidepressants and counseling. Exercise can help stop weight gain and the loss of bone and muscle mass. Exercise also reduces fatigue.
Chemotherapy Side Effects
Chemotherapy
is the use of drugs to treat
cancer. Chemotherapy is sometimes
used if prostate cancer has spread outside
of the prostate gland and hormone
therapy is not working.
Side effects of chemotherapy depend on the type of chemotherapy you receive, the amount taken, and the length of treatment. Some side effects of chemotherapy include nausea and vomiting; loss of appetite; hair loss; sore mouth, gums, or throat; dry skin; increased chance of bruising and bleeding; infection; and fatigue. If you have side effects from chemotherapy, talk with your doctor, as there is help for many side effects caused by chemotherapy.
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Source: Excerpted with permission from www.cancer.net, copyright © 2009 American Society of Clinical Oncology. All rights reserved.
This article was originally published in Coping® with Cancer magazine, September/October 2009.

